I-Chun Cheng's research interests are mainly in novel silicon materials and flexible large-area electronics. Her work includes: nanocrystalline silicon thin film and device structure studies, preparation techniques of flexible organic polymer substrates and flexible metal foil substrates, development of amorphous and nanocrystalline silicon thin-film-transistor technology and active matrix electronics on flexible substrates, thin film mechanics and stress control of the film-on-foil system, device physics in flexible electronics, particularly in the interdependence of electrical and mechanical properties.