My research interests focus on biomedical applications of ultrasonic imaging with emphasis on the underlying physics and signal processing algorithms. The ultimate goal is to improve the clinical and research value of biomedical ultrasound. The current research topics include:
Nonlinear ultrasonic imaging: Ultrasonic nonlinear imaging is based on the finite amplitude distortion during acoustic propagation. The purpose of this research is to understand the imaging mechanism and to propose new imaging techniques. This research is also related to nonlinear imaging using contrast agents, and molecular imaging and gene therapy using sub-micron particles.
High frequency imaging: Small animal models are often used in gene research, developmental biology and drug development. A non-invasive imaging system with adequate resolution and sensitivity is of particular importance. The use of high frequency ultrasound in this area still has several problems to overcome, including the improvement in resolution and the development of new blood flow estimation techniques.
Elasticity imaging: The purpose of elasticity imaging is to develop a new imaging method that can evaluate tissue pathological status, assess mechanical properties of blood vessels and provide new diagnostic information in rehabilitation. The focus of this research is strain imaging of tendon, the change in elastic properties of liver cirrhosis and strain compounding.
Digital beamformer design: The advance of medical ultrasonic imaging system technologies is closely linked to the advance in electronic technologies. It is also expected that the foreseeable new electronic technologies can continue to benefit performance of ultrasonic imaging. This research covers the application of DS-modulator in digital beamforming, and the dynamic focus control methods for 3D imaging using 2D arrays.