李心予教授的簡傳 - Biography of Hsinyu Lee

李心予 Hsinyu Lee

Photo of Hsinyu Lee

Prof. Hsinyu Lee’s research is focused on cell biology related topics. His major research interest is to investigate the effects of lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) in endothelial cells. LPA and S1P are two low molecular weight lysophospholipids (LPLs) derived from enzymatic cleavage of membrane phospholipids which are highly enriched in serum.  In the past 10 years, he demonstrated that LPLs are important regulators for inflammation processes.  His most recent findings suggested that LPA is also an important regulator for lymphatic vessel development. These results strongly suggested that LPLs might be important regulators for cancer metastasis, tumor development and cancer cell survival. Through collaboration with colleagues at NTU hospital, he extended his research to identify neuroblastoma, hepatoma and gastric cancer related cancer markers and exploring their potential roles in tumor formation.  He published 46 related papers in the past five years.  He received the Excellence Teaching Awards from National Taiwan University and also from the Department of Education, ROC for his contribution in general education in NTU. He has served as reviewer for top journals such as Blood, FASEB J, CMLS and Oncogenes.