Non-invasive, minimally invasive, and targeted therapy are the focus of future research and development in therapeutic medicine. The major research direction of this research team is to design and develop medical equipment related to biological system control, including: (1) development of therapeutic ultrasound for the application of related biological system control of the brain technology development, (2) augmented reality/ mixed reality assisted medical surgical intervention assistance, and (3) technology development for minimally invasive surgery guidance.